/* Validation uses the same restrained tool surfaces as the molecular workspaces. */
.validation-main{padding:24px 0 0}.validation-main>.wide{max-width:1440px;padding:0 32px}.validation-comparison,.validation-evidence{background:#fff;border:1px solid var(--rule);border-radius:4px;min-width:0}.validation-heading{display:flex;justify-content:space-between;align-items:center;gap:20px;padding:18px 20px}.validation-heading>div{display:flex;align-items:baseline;gap:16px;flex-wrap:wrap}.validation-heading h1,.validation-heading h2{font-size:15px;font-weight:600;letter-spacing:0;margin:0;line-height:1.5}.validation-heading span{font-size:var(--text-small);color:var(--mut)}.validation-heading button{font-size:var(--text-small);white-space:nowrap}.validation-switches{padding-top:8px;display:flex;justify-content:space-between;gap:16px;align-items:center;padding:0 20px;border-bottom:1px solid var(--rule)}.dataset-tabs,.evidence-tabs{display:flex;gap:24px;min-width:0}.dataset-tabs button,.evidence-tabs button{border:0;border-bottom:2px solid transparent;border-radius:0;background:none;color:var(--mut);padding:10px 0 12px;font-size:var(--text-ui);cursor:pointer;white-space:nowrap;transition:color 150ms,border-color 150ms}.dataset-tabs button:hover,.evidence-tabs button:hover{color:var(--teal)}.dataset-tabs button[aria-selected=true],.evidence-tabs button[aria-selected=true]{border-bottom-color:var(--teal2);color:var(--teal);font-weight:600}.evaluation-scope{padding:14px 20px 0;display:flex;justify-content:space-between;gap:12px;font-size:var(--text-small);color:var(--mut);flex-wrap:wrap}.validation-metrics{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));margin:16px 20px 20px}.validation-metrics>div{padding:0 20px;border-left:1px solid var(--rule)}.validation-metrics>div:first-child{padding-left:0;border-left:0}.validation-metrics dt{font-size:var(--text-small);color:var(--mut)}.validation-metrics dd{font:500 27px/1.5 var(--mono);margin:3px 0;color:var(--ink)}.validation-metrics>div:first-child dd,.validation-metrics>div:last-child dd{color:var(--teal)}.validation-metrics span{font-size:var(--text-small);color:var(--mut)}.validation-table-scroll{overflow:auto;max-height:530px;overscroll-behavior:contain}.validation-main table.b{width:100%;min-width:600px;margin:0;table-layout:auto;border-collapse:separate;border-spacing:0}.validation-main table.b th,.validation-main table.b td{padding:11px 20px;font-size:var(--text-ui);letter-spacing:0;text-transform:none;border-bottom:1px solid var(--rule);white-space:nowrap}.validation-main table.b thead th{position:sticky;top:0;z-index:1;background:#F4F8F8;color:#4A6068;font:500 var(--text-small) var(--sans)}.validation-main table.b thead th.n,.validation-main table.b td.n{text-align:right}.validation-main table.b th[scope=row]{background:transparent;color:var(--ink);font:500 12px var(--sans)}.validation-main table.b .model-input{font-size:var(--text-small);color:var(--mut)}.validation-main table.b tbody tr:last-child :is(th,td){border-bottom:0}.validation-main table.b tr.best :is(th,td){background:#EAF3F3}.validation-main table.b tr:hover :is(th,td){background:#F6F9F9}.validation-main table.b tr.best:hover :is(th,td){background:#E4EFEF}.ap-reading{display:inline-flex;align-items:center;gap:14px}.ap-reading i{width:62px;height:4px;background:linear-gradient(to right,#B8C9CD var(--ap),#EDF1F2 var(--ap));display:inline-block}.best .ap-reading i{background:linear-gradient(to right,var(--teal2) var(--ap),#DBE5E7 var(--ap))}.ap-reading b{font-weight:500;min-width:48px}.comparison-note{padding:12px 20px;display:flex;justify-content:space-between;align-items:baseline;gap:12px;border-top:1px solid var(--rule);font-size:var(--text-small);color:var(--mut)}.comparison-note a{white-space:nowrap;border:0}.validation-evidence{margin-top:24px}.evidence-tabs{padding:0 20px;border-bottom:1px solid var(--rule)}.evidence-body{padding:18px 20px 20px}.chart-context{display:flex;justify-content:space-between;gap:12px;font-size:var(--text-small);color:var(--mut);flex-wrap:wrap;margin-bottom:18px}.histogram-frame{display:grid;grid-template-columns:42px minmax(0,1fr);gap:12px;margin:4px 0 14px}.histogram-axis{height:220px;display:flex;flex-direction:column;justify-content:space-between;align-items:flex-end;font:var(--text-small) var(--mono);color:var(--mut);padding-top:0}.validation-page .validation-hist{height:220px;padding-top:0;gap:4px;background:repeating-linear-gradient(to top,transparent 0,transparent calc(25% - 1px),#EEF2F3 calc(25% - 1px),#EEF2F3 25%)}.validation-page .distribution-bin{background:transparent;border:0;padding:0;border-radius:0;position:relative;outline-offset:1px}.validation-page .distribution-bin i{min-height:0;flex:none;width:100%}.validation-page .distribution-bin:hover,.validation-page .distribution-bin:focus-visible{background:#164E590D}.validation-page .distribution-bin.is-active{outline:1px solid var(--teal2);outline-offset:1px}.validation-page .distribution-threshold{border-left-color:var(--teal);z-index:1}.threshold-caption{position:absolute;top:-17px;left:58.4%;font:var(--text-small) var(--mono);color:var(--teal);transform:translateX(-50%);white-space:nowrap}.validation-page .histx{font-size:var(--text-small);margin-top:8px}.chart-readout{font:var(--text-small)/1.7 var(--mono);color:var(--ink);min-height:22px}.validation-page .distribution-legend{gap:20px;color:var(--mut);font-size:var(--text-small);margin-top:10px}.distribution-legend>span{display:inline-flex;align-items:center;gap:7px}.distribution-legend>span::before{content:'';width:9px;height:9px;background:#C9D6DB}.distribution-legend .legend-positive::before{background:var(--teal2)}.distribution-legend .legend-threshold::before{height:12px;width:0;background:none;border-left:1px dashed var(--teal)}.chart-note{font-size:var(--text-small);color:var(--mut);line-height:1.85;margin:14px 0 0;max-width:100ch;text-wrap:pretty}#pr{display:block;width:100%;height:auto;max-height:475px}.validation-page .lg{font-size:var(--text-small);gap:18px;color:var(--mut);margin-top:0}.lg .pr-ours{border-color:#164E59}.lg .pr-baseline{border-color:#718C94;border-top-style:dashed}.lg .pr-rate{border-color:#AF3935;border-top-style:dashed}.validation-analyses{margin:16px 0}.validation-disclosure{border-bottom:1px solid var(--rule)}.validation-disclosure>summary{display:flex;align-items:center;gap:6px;padding:10px 0;cursor:pointer;list-style:none;font-size:13px;color:var(--ink)}.validation-disclosure>summary::-webkit-details-marker{display:none}.validation-disclosure>summary::before{content:'›';font-size:17px;line-height:1;transition:transform 180ms;color:var(--mut)}.validation-disclosure[open]>summary::before{transform:rotate(90deg)}.validation-disclosure small{margin-left:auto;font-size:var(--text-small);color:var(--mut);font-weight:400}.disclosure-body{padding:0 0 20px;animation:evidence-reveal 180ms ease-out}.disclosure-body>.tw,.disclosure-body>.validation-table-scroll{border:1px solid var(--rule);border-radius:3px;background:white;overflow:auto}.analysis-context{font-size:var(--text-small);color:var(--mut);margin-bottom:12px}.validation-main .ci{font:var(--text-small) var(--mono);color:var(--mut)}.validation-main .delta{font:12px var(--mono)}.validation-method{scroll-margin-top:20px;background:transparent;border:0;border-radius:0}.validation-method>summary{padding:10px 0}.validation-method>summary::before{flex:0 0 8px}.validation-method>.disclosure-body{padding:0 0 12px 14px}.validation-method .method-columns{border:0;background:transparent}.validation-method .method-columns>div{padding:2px 16px 0 0}.validation-method .method-columns>div+div{padding:2px 0 0 16px}.method-columns{display:grid;grid-template-columns:minmax(0,1.35fr) minmax(0,1fr);border-top:1px solid var(--rule)}.method-columns>div{padding:20px}.method-columns>div+div{border-left:1px solid var(--rule)}.method-columns h3{font-size:13px;font-weight:600;margin:0 0 10px}.method-columns dl>div{display:grid;grid-template-columns:65px minmax(0,1fr);gap:14px;margin-top:10px;font-size:var(--text-ui);line-height:1.8}.method-columns dt{color:var(--mut);font-size:var(--text-small)}.method-columns dd{max-width:70ch}.interpretation-limits p,.interpretation-limits li{font-size:var(--text-ui);line-height:1.9;max-width:65ch}.interpretation-limits ul{padding-left:17px;margin:14px 0 18px}.interpretation-limits li+li{margin-top:8px}.interpretation-limits a{font-size:var(--text-ui);border:0}.validation-main .workspace-footer{margin-top:28px}.validation-page [role=tabpanel]:not([hidden]){animation:evidence-reveal 180ms ease-out}@keyframes evidence-reveal{from{opacity:.6}to{opacity:1}}@media(max-width:700px){.validation-main{padding-top:16px}.validation-main>.wide{padding:0 16px}.validation-heading{padding:15px 14px;align-items:flex-start}.validation-heading>div{display:block}.validation-heading h1,.validation-heading h2{font-size:14px}.validation-heading span{display:block;margin-top:5px;font-size:var(--text-small)}.validation-switches{padding:0 14px;flex-wrap:wrap;gap:0}.dataset-tabs{gap:18px}.dataset-tabs button,.evidence-tabs button{font-size:var(--text-small)}.evaluation-scope{padding:12px 14px 0;font-size:var(--text-small);gap:4px}.validation-metrics{grid-template-columns:1fr 1fr;gap:18px 0;margin:16px 14px}.validation-metrics>div{padding-left:14px}.validation-metrics>div:nth-child(3){padding-left:0;border-left:0}.validation-metrics dd{font-size:23px}.validation-metrics dt,.validation-metrics span{font-size:var(--text-small)}.validation-main table.b th,.validation-main table.b td{padding:10px 14px;font-size:var(--text-small)}.validation-main table.b{min-width:550px}.validation-table-scroll{max-height:470px}.comparison-note{padding:12px 14px;flex-wrap:wrap;font-size:var(--text-small)}.validation-evidence{margin-top:18px}.evidence-tabs{gap:18px;padding:0 14px}.evidence-body{padding:16px 14px}.chart-context{font-size:var(--text-small);gap:5px}.histogram-frame{grid-template-columns:30px minmax(0,1fr);gap:8px;margin-top:26px}.validation-page .validation-hist{gap:2px;height:180px}.histogram-axis{height:180px;font-size:var(--text-small)}.validation-page .histx{font-size:var(--text-small)}.chart-readout{font-size:var(--text-small);min-height:36px}.validation-page .distribution-legend{gap:12px;font-size:var(--text-small)}.chart-note{font-size:var(--text-small)}.validation-page .lg{font-size:var(--text-small);gap:8px 16px}#pr{max-height:none}.validation-disclosure small{font-size:var(--text-small);max-width:48%;text-align:right}.validation-disclosure>summary{font-size:var(--text-ui)}.validation-method>summary{padding:10px 0}.validation-method>.disclosure-body{padding:0 0 12px 14px}.validation-method .method-columns>div{padding:2px 0 0}.validation-method .method-columns>div+div{margin-top:12px;padding:12px 0 0}.method-columns{grid-template-columns:minmax(0,1fr)}.method-columns>div{padding:18px 14px}.method-columns>div+div{border-left:0;border-top:1px solid var(--rule)}.method-columns dl>div{grid-template-columns:55px minmax(0,1fr);gap:12px}.validation-main .workspace-footer{padding:18px 0}.validation-main .workspace-footer a{margin-left:auto}}
@media(prefers-reduced-motion:reduce){.validation-page [role=tabpanel],.disclosure-body{animation:none}.validation-disclosure>summary::before{transition:none}}

.validation-metrics span{display:block}
.table-scroll-hint{display:none}
@media(max-width:700px){
 .table-scroll-hint{display:block;flex-basis:100%;font-size:var(--text-small);line-height:1.8;color:var(--mut);margin:0}
 .validation-main table.b :is(th,td):first-child{position:sticky;left:0;z-index:1;background:var(--paper);box-shadow:1px 0 var(--rule);min-width:110px}
 .validation-main table.b thead th:first-child{z-index:3;background:#F4F5F7}
 .validation-main table.b tr.best th:first-child{background:var(--selected)}
}